Hyaluronic Acid
INCI: Sodium hyaluronate
Hyaluronic Acid (sodium hyaluronate) is a glycosaminoglycan naturally found in skin, joints, and connective tissue. In gummy formats it is most commonly used in beauty and nutricosmetics ranges for skin hydration and elasticity, often paired with Collagen and Vitamin C. HA itself has no authorised EU health claim under Reg. 432/2012; claim coverage derives from co-formulated nutrients.
- Skin hydration
- Beauty stacks
- Joint comfort
At a glance
- Definition
- Hyaluronic Acid (sodium hyaluronate) is a glycosaminoglycan naturally found in skin, joints, and connective tissue. In gummy formats it is most commonly used in beauty and nutricosmetics ranges for skin hydration and elasticity, often paired with Collagen and Vitamin C. HA itself has no authorised EU health claim under Reg. 432/2012; claim coverage derives from co-formulated nutrients.
- Authorised wording (summary)
- 3 authorised statements — see "US structure-function statements" below.
- Common positionings
- Skin hydration and beauty
- Joint comfort
- Healthy ageing
- Premium nutricosmetics
- Format suitability
- Reviewed for gummies and sachets — confirmed per project.
Where this ingredient fits in the DAT Supply catalogue
Every format chip links through to its manufacturing hub and to the private-label catalogue for that format. The category chip routes to the matching vertical hub on the categories index.
- Beauty & skin
- Browse all ingredients
What it is
Hyaluronic Acid (sodium hyaluronate) is a glycosaminoglycan naturally found in skin, joints, and connective tissue. In gummy formats it is most commonly used in beauty and nutricosmetics ranges for skin hydration and elasticity, often paired with Collagen and Vitamin C. HA itself has no authorised EU health claim under Reg. 432/2012; claim coverage derives from co-formulated nutrients.
For private-label brands, hyaluronic acid is a premium active in beauty gummy ranges.
Why brands use Hyaluronic Acid
Hyaluronic Acid is one of the most familiar and commercially understood actives in its category across EU and US markets. Pairs naturally with Collagen and Vitamin C for beauty stacks (synergistic in collagen formation); with Biotin and Zinc for hair-skin-nails; with Glucosamine for joint positioning.
Consumer-perceived effective dose: 80–200 mg per daily serving for skin positioning. Gummy formats handle this comfortably. DAT reviews wording per project against Reg. 1924/2006 and the authorised list under Reg. 432/2012.
Formats this ingredient is reviewed for
DAT Supply covers gummy, capsule, softgel, tablet, powder, oral strip, liquid drop, shot, jelly and pet formats. The list below reflects every format this ingredient is reviewed for — chips link through to the manufacturing hub for each format. Final compatibility, dose and matrix are confirmed per project.
Formulation notes
Verified formulation reference across the formats this ingredient is reviewed for — the Supported formats section lists every product format this active is approved for, and the per-format Considerations section below covers matrix-specific guidance. Final formulation, dose and on-pack copy are confirmed per project.
- Gummy fit
- Good
- Heat stable
- Yes
- Soluble in matrix
- Yes
- Cost tier
- High
Forms available
- Sodium hyaluronate (low / medium / high molecular weight)
- Hyaluronic acid + collagen complexes
Dosage reference
Consumer-perceived effective dose: 80–200 mg per daily serving for skin positioning. Gummy formats handle this comfortably.
Taste & sensory
Effectively tasteless at typical gummy doses.
Manufacturing notes
Fermentation-derived sodium hyaluronate is the standard for vegan-positioned ranges. Low-molecular-weight HA is absorbed more efficiently; medium/high MW positions for skin barrier support. Vegan / kosher / halal positioning depends on the selected raw material and supplier documentation — confirmed per project.
Per-format formulation notes
Safe-baseline considerations for each format this ingredient is reviewed for. Final formulation, dose and on-pack copy are confirmed per project.
Gummies
- Taste masking and aroma load against the cooked-base flavour — confirmed per project.
- Heat exposure during cooking; coated or encapsulated forms may be required — confirmed per project.
- Matrix choice (pectin vs gelatin) and its effect on ingredient stability — confirmed per project.
- Per-gummy dose and serving count needed to hit the label claim — confirmed per project.
Sachets
- Powder flow and dose accuracy at single-serve sachet weights — confirmed per project.
- Barrier requirements (oxygen, moisture) for the active — confirmed per project.
- Reconstitution behaviour when the sachet is dosed into water — confirmed per project.
US structure-function statements
- Hyaluronic Acid supports skin hydrationStructure-function (DSHEA)
- Hyaluronic Acid supports joint comfortStructure-function (DSHEA)
- Hyaluronic Acid supports healthy skinStructure-function (DSHEA)
Structure-function statements must appear with the FDA disclaimer in the same field of vision on the label. % Daily Value (DV) based on FDA 21 CFR 101.9.
Wording to avoid on pack copy
- No disease claims.
- Structure-function claims must be accompanied by the FDA disclaimer.
- No certification promises (vegan / kosher / halal / organic / non-GMO) on pack until per-project and per-batch supplier documentation is confirmed.
- No guaranteed shelf-life on pack until confirmed per project with stability data.
These statements have not been evaluated by the FDA. There is no FDA-established Daily Value for Hyaluronic Acid.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Studies & evidence
External peer-reviewed sources and regulatory opinions. Citations only — DAT does not endorse the publishers.
Oe M, Sakai S, Yoshida H et al.·Clinical, Cosmetic and Investigational Dermatology·2017
European Commission·EUR-Lex·2012
Product concepts featuring Hyaluronic Acid
Private-label product concepts where Hyaluronic Acid appears in the formula. Each opens to a product brief and quote route.
Hyaluronic Glow Gummies
Private label hyaluronic glow gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Radiance & Youth Gummies
Private label radiance & youth gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Sleep & Skin Recovery Gummies
Private label sleep & skin recovery gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Collagen Gummies
Private label collagen gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Synergies & conflicts
Pairs well with
Pairs naturally with Collagen and Vitamin C for beauty stacks (synergistic in collagen formation); with Biotin and Zinc for hair-skin-nails; with Glucosamine for joint positioning.
Care when combining with
Generally safe and well-tolerated; rare allergic reactions in chicken-comb-derived HA — fermentation-derived HA avoids this concern.
Similar ingredients
Ingredients that frequently sit alongside this one in private-label supplement briefs.
Chondroitin Sulfate
Chondroitin sulfate is a naturally occurring glycosaminoglycan found in cartilage and connective tissue. It is one of the most familiar and commercially understood joint health actives across EU and US markets. Chondroitin sulfate has no authorised health claims under Reg. (EU) 432/2012, so brands typically position it alongside co-formulated nutrients such as Vitamin C (for collagen formation) or Vitamin D (for normal bone function). It is not suitable for gummy formats due to poor solubility and high molecular weight, and is typically delivered in sachet formats.
Coenzyme Q10
Coenzyme Q10 is used in private-label supplement manufacturing. Sourcing, dose anchors and target-market documentation are reviewed per project.
Dihydroberberine
Dihydroberberine is a reduced form of berberine, a naturally occurring alkaloid found in plants such as Berberis aristata and Coptis chinensis. It is used in dietary supplements for metabolic wellness and blood sugar balance positioning. As a botanical-derived compound on the EU on-hold list, it has no authorised health claims under Reg. (EU) 432/2012.
Glucosamine Sulfate
Glucosamine is a naturally occurring amino sugar that is a structural component of cartilage and synovial fluid. In supplement form (sulfate or hydrochloride), it has been used for decades in joint-positioned ranges. Glucosamine itself has no authorised EU health claim under Reg. 432/2012; in gummy formats it is most commonly positioned for 'joint comfort' alongside co-formulated nutrients that carry authorised claims.
Lutein
Lutein is a carotenoid pigment found naturally in green leafy vegetables and egg yolks. It is one of the most familiar and commercially understood gummy actives across EU and US markets, primarily positioned for eye and macular health. Lutein has no authorised health claim under Reg. (EU) 432/2012; any claim coverage relies on co-formulated nutrients.
Melatonin
Melatonin is a hormone naturally produced by the pineal gland that regulates circadian rhythm and sleep onset. In food-supplement gummy formats it is the most commonly requested sleep-onset active, with two EU-authorised health claims under Reg. 432/2012 at 1 mg (sleep onset) and 0.5 mg (jet lag) per portion. Above these doses, EU classification typically shifts to medicinal product — Member State verification is required per project.
Adjacent reading
Pairings, resource guides and blog notes most often associated with Hyaluronic Acid on DAT Supply briefs.
Develop a formula featuring Hyaluronic Acid
A ready white-label formula exists — open a product brief, or talk to our team to align the launch plan.